| 09/02/06 | hosting | Florida Atlantic | 54-6 |
| 09/09/06 | at | Boston College | 33-34 2OT |
| 09/16/06 | at | Florida St | 27-20 |
| 09/23/06 | hosting | North Carolina | 52-7 |
| 09/30/06 | hosting | Louisiana Tech | 51-0 |
| 10/07/06 | at | Wake Forest | 27-17 |
| 10/12/06 | hosting | Temple | 63-9 |
| 10/21/06 | hosting | Georgia Tech | 31-7 |
| 10/26/06 | at | Virginia Tech | 7-24 |
| 11/04/06 | hosting | Maryland | 12-13 |
| 11/11/06 | hosting | North Carolina St | 20-14 |
| 11/25/06 | hosting | South Carolina | 28-31 |
| 12/29/06 | at | Kentucky | 20-28 |