| 09/02/06 | at | Rice | 31-30 |
| 09/09/06 | hosting | Tulane | 45-7 |
| 09/16/06 | hosting | Grambling St | 42-22 |
| 09/23/06 | hosting | Oklahoma St | 34-25 |
| 09/30/06 | at | Miami FL | 13-14 |
| 10/07/06 | hosting | Louisiana-Lafayette | 28-31 |
| 10/14/06 | at | Southern Miss | 27-31 |
| 10/21/06 | hosting | UTEP | 34-17 |
| 10/28/06 | hosting | Central Florida | 51-31 |
| 11/04/06 | hosting | Tulsa | 27-10 |
| 11/11/06 | at | SMU | 37-27 |
| 11/18/06 | at | Memphis | 23-20 OT |
| 12/01/06 | hosting | Southern Miss | 34-20 |
| 12/29/06 | hosting | South Carolina | 36-44 |