| 09/02/06 | hosting | Northwestern St | 49-18 |
| 09/09/06 | hosting | Louisiana-Monroe | 21-19 |
| 09/15/06 | at | Toledo | 31-37 2OT |
| 09/23/06 | hosting | South Florida | 13-7 |
| 09/30/06 | at | Nebraska | 32-39 |
| 10/07/06 | hosting | Texas A&M | 18-21 |
| 10/14/06 | hosting | Oklahoma St | 32-42 |
| 10/21/06 | at | Baylor | 35-36 |
| 10/28/06 | hosting | Colorado | 20-15 |
| 11/04/06 | at | Iowa St | 41-10 |
| 11/18/06 | hosting | Kansas St | 39-20 |
| 11/25/06 | at | Missouri | 17-42 |