| 09/02/06 | at | Southern Virginia | 24-17 |
| 09/09/06 | hosting | Austin Peay | 21-28 |
| 09/23/06 | at | Virginia-Wise | 42-59 |
| 09/30/06 | hosting | Lambuth | 24-41 |
| 10/07/06 | hosting | West Virginia Tech | 42-7 |
| 10/14/06 | at | Pikeville | 38-41 |
| 10/21/06 | hosting | Campbellsville | 27-7 |
| 10/26/06 | at | Shorter | 10-30 |
| 11/04/06 | hosting | Bethel TN | 7-28 |
| 11/11/06 | at | Belhaven | 7-39 |