| 09/02/06 | hosting | Northeastern | 38-0 |
| 09/09/06 | at | North Carolina | 35-10 |
| 09/16/06 | hosting | Duke | 36-0 |
| 09/23/06 | hosting | Cincinnati | 29-13 |
| 09/30/06 | hosting | Georgia Tech | 27-38 |
| 10/12/06 | at | Boston College | 3-22 |
| 10/21/06 | hosting | Southern Miss | 36-6 |
| 10/26/06 | hosting | Clemson | 24-7 |
| 11/04/06 | at | Miami FL | 17-10 |
| 11/11/06 | hosting | Kent St | 23-0 |
| 11/18/06 | at | Wake Forest | 27-6 |
| 11/25/06 | hosting | Virginia | 17-0 |
| 12/30/06 | at | Georgia | 24-31 |