| 11/14/05 | hosting | Drexel | 41-54 |
| 11/20/05 | at | Lehigh | 64-54 |
| 11/27/05 | hosting | Lafayette | 46-57 |
| 12/03/05 | at | Colgate | 39-62 |
| 12/06/05 | hosting | Temple | 47-60 |
| 12/10/05 | hosting | Wyoming | 59-50 |
| 12/14/05 | hosting | Monmouth | 21-41 |
| 12/17/05 | at | Wake Forest | 42-61 |
| 12/21/05 | vs. | Stanford | 34-58 |
| 12/28/05 | hosting | Carnegie Mellon | 46-51 |
| 12/31/05 | at | Rutgers | 44-54 |
| 01/05/06 | at | Rice | 41-52 |
| 01/13/06 | hosting | Columbia | 68-64 OT |
| 01/14/06 | hosting | Cornell | 49-57 |
| 01/29/06 | at | Davidson | 50-65 |
| 02/03/06 | hosting | Yale | 66-49 |
| 02/04/06 | hosting | Brown | 52-37 |
| 02/10/06 | at | Harvard | 60-59 |
| 02/11/06 | at | Dartmouth | 52-49 |
| 02/14/06 | at | Pennsylvania | 41-60 |
| 02/17/06 | at | Cornell | 76-68 2OT |
| 02/18/06 | at | Columbia | 64-65 |
| 02/24/06 | hosting | Dartmouth | 63-60 |
| 02/25/06 | hosting | Harvard | 75-48 |
| 03/03/06 | at | Brown | 46-61 |
| 03/04/06 | at | Yale | 56-45 |
| 03/07/06 | hosting | Pennsylvania | 60-59 OT |