| 11/02/05 | hosting | Charlotte | 109-105 OT |
| 11/05/05 | at | New Jersey | 99-100 |
| 11/07/05 | hosting | San Antonio | 95-104 OT |
| 11/09/05 | hosting | Golden State | 85-84 |
| 11/12/05 | hosting | Utah | 103-98 |
| 11/14/05 | at | Golden State | 82-100 |
| 11/16/05 | at | Portland | 93-96 |
| 11/18/05 | at | Seattle | 84-98 |
| 11/20/05 | at | L.A. Lakers | 96-93 |
| 11/25/05 | at | San Antonio | 106-99 |
| 11/26/05 | at | Houston | 94-89 |
| 11/29/05 | hosting | Orlando | 85-76 |
| 11/30/05 | at | New York | 101-109 |
| 12/02/05 | at | Boston | 106-102 |
| 12/03/05 | hosting | Detroit | 79-92 |
| 12/05/05 | hosting | Dallas | 94-102 |
| 12/07/05 | at | Orlando | 102-93 |
| 12/09/05 | hosting | L.A. Lakers | 80-93 |
| 12/10/05 | at | Washington | 118-111 |
| 12/13/05 | hosting | Miami | 97-100 |
| 12/14/05 | at | Toronto | 105-94 |
| 12/16/05 | at | Detroit | 82-110 |
| 12/17/05 | hosting | Boston | 118-86 |
| 12/20/05 | hosting | Charlotte | 92-105 |
| 12/22/05 | hosting | Cleveland | 100-108 |
| 12/23/05 | at | Memphis | 77-95 |
| 12/26/05 | at | Cleveland | 91-102 |
| 12/28/05 | at | Charlotte | 80-93 |
| 12/31/05 | hosting | Phoenix | 98-107 OT |
| 01/02/06 | hosting | Milwaukee | 92-93 |
| 01/04/06 | hosting | Seattle | 97-101 |
| 01/06/06 | at | Milwaukee | 105-91 |
| 01/07/06 | hosting | Memphis | 111-82 |
| 01/09/06 | hosting | Toronto | 113-104 |
| 01/11/06 | at | Minnesota | 93-99 |
| 01/14/06 | hosting | Indiana | 89-91 |
| 01/16/06 | hosting | Denver | 94-97 |
| 01/18/06 | hosting | New York | 106-104 OT |
| 01/20/06 | hosting | Houston | 108-109 2OT |
| 01/21/06 | at | Indiana | 101-89 |
| 01/25/06 | at | Toronto | 104-88 |
| 01/27/06 | hosting | Washington | 90-79 |
| 01/28/06 | hosting | Atlanta | 111-99 |
| 01/31/06 | at | Dallas | 94-98 |
| 02/01/06 | at | New Orleans/Okla Cty | 95-100 |
| 02/04/06 | at | Phoenix | 101-118 |
| 02/06/06 | at | Utah | 107-109 OT |
| 02/08/06 | at | Denver | 110-107 |
| 02/09/06 | at | Sacramento | 80-98 |
| 02/12/06 | at | L.A. Clippers | 97-91 |
| 02/14/06 | hosting | Sacramento | 101-105 OT |
| 02/16/06 | hosting | Philadelphia | 117-84 |
| 02/22/06 | hosting | Milwaukee | 97-91 |
| 02/24/06 | hosting | Detroit | 87-95 |
| 02/25/06 | at | Philadelphia | 102-108 |
| 02/28/06 | hosting | Minnesota | 111-100 |
| 03/02/06 | hosting | Cleveland | 91-92 |
| 03/03/06 | at | New York | 108-101 |
| 03/05/06 | at | Cleveland | 72-91 |
| 03/07/06 | hosting | New Jersey | 95-87 |
| 03/08/06 | at | Detroit | 101-106 |
| 03/10/06 | hosting | L.A. Clippers | 96-107 |
| 03/11/06 | at | Atlanta | 95-90 |
| 03/14/06 | hosting | Portland | 95-66 |
| 03/15/06 | at | Milwaukee | 88-104 |
| 03/18/06 | hosting | Miami | 84-85 |
| 03/19/06 | at | Washington | 104-113 |
| 03/22/06 | at | Indiana | 85-95 |
| 03/24/06 | hosting | New Orleans/Okla Cty | 96-82 |
| 03/26/06 | at | Boston | 101-97 |
| 03/28/06 | hosting | Orlando | 93-97 |
| 03/31/06 | at | Charlotte | 113-107 |
| 04/01/06 | hosting | Boston | 100-94 |
| 04/04/06 | hosting | Indiana | 102-96 |
| 04/05/06 | at | Philadelphia | 99-92 |
| 04/08/06 | hosting | Philadelphia | 75-89 |
| 04/11/06 | hosting | New Jersey | 104-101 |
| 04/12/06 | at | Atlanta | 96-90 |
| 04/14/06 | hosting | Washington | 103-101 |
| 04/16/06 | at | Miami | 117-93 |
| 04/17/06 | at | Orlando | 116-112 OT |
| 04/19/06 | hosting | Toronto | 127-106 |
| 04/22/06 | at | Miami | 106-111 |
| 04/24/06 | at | Miami | 108-115 |
| 04/27/06 | hosting | Miami | 109-90 |
| 04/30/06 | hosting | Miami | 93-87 |
| 05/02/06 | at | Miami | 78-92 |
| 05/04/06 | hosting | Miami | 96-113 |