| (48.26) | ||||
| 09/12/11 | hosting | Oakland | (48.36) | 20-23 |
| 09/18/11 | hosting | Cincinnati | (49.15) | 24-22 |
| 09/25/11 | at | Tennessee | (49.35) | 14-17 |
| 10/02/11 | at | Green Bay | (53.09) | 23-49 |
| 10/09/11 | hosting | San Diego | (50.36) | 24-29 |
| 10/23/11 | at | Miami | (50.36) | 18-15 OT |
| 10/30/11 | hosting | Detroit | (50.73) | 10-45 |
| 11/06/11 | at | Oakland | (48.36) | 38-24 |
| 11/13/11 | at | Kansas City | (48.45) | 17-10 |
| 11/17/11 | hosting | N.Y. Jets | (50.33) | 17-13 |
| 11/27/11 | at | San Diego | (50.36) | 16-13 OT |
| 12/04/11 | at | Minnesota | (47.18) | 35-32 |
| 12/11/11 | hosting | Chicago | (49.57) | 13-10 OT |
| 12/18/11 | hosting | New England | (54.18) | 23-41 |
| 12/24/11 | at | Buffalo | (48.17) | 14-40 |
| 01/01/12 | hosting | Kansas City | (48.45) | 3-7 |
| 01/08/12 | hosting | Pittsburgh | (51.85) | 29-23 OT |
| 01/14/12 | at | New England | (54.18) | 10-45 |