| 08/25/05 | vs. | Central Arkansas | 0-51 |
| 09/03/05 | hosting | SE Oklahoma St | 12-28 |
| 09/10/05 | at | SW Oklahoma St | 28-0 |
| 09/17/05 | hosting | East Central OK | 30-13 |
| 09/24/05 | at | Abilene Christian | 33-30 |
| 10/01/05 | hosting | Angelo St | 38-14 |
| 10/08/05 | at | West Texas A&M | 51-52 |
| 10/15/05 | hosting | Tarleton St | 27-34 |
| 10/22/05 | at | TAMU-Kingsville | 14-26 |
| 10/29/05 | hosting | Midwestern St | 27-62 |
| 11/05/05 | at | Western New Mexico | 47-20 |