| 08/26/05 | at | Bentley | 72-17 |
| 09/03/05 | hosting | Edinboro | 23-21 |
| 09/10/05 | at | C.W. Post | 66-49 |
| 09/24/05 | at | Millersville | 17-13 |
| 10/01/05 | hosting | Bloomsburg | 24-31 |
| 10/08/05 | at | Clarion | 56-0 |
| 10/15/05 | hosting | Kutztown | 42-14 |
| 10/22/05 | at | West Chester | 17-18 |
| 10/29/05 | at | Cheyney | 40-3 |
| 11/05/05 | hosting | Mansfield | 57-20 |
| 11/12/05 | hosting | Southern Conn St | 55-33 |
| 11/19/05 | at | Bloomsburg | 52-39 |
| 11/26/05 | hosting | C.W. Post | 55-28 |
| 12/03/05 | at | Grand Valley St | 20-55 |