| 09/10/05 | at | Davidson | 7-32 |
| 09/17/05 | at | Maryville | 27-35 |
| 09/24/05 | at | Southern Virginia | 7-35 |
| 10/01/05 | hosting | Guilford | 35-36 |
| 10/08/05 | hosting | Christopher Newport | 15-28 |
| 10/15/05 | at | Shenandoah | 34-27 |
| 10/22/05 | hosting | Averett | 20-21 |
| 10/29/05 | at | Ferrum | 0-55 |
| 11/05/05 | hosting | Methodist | 21-45 |
| 11/12/05 | hosting | North Carolina Wesleyan | 21-28 |