| 08/27/05 | hosting | Delta St | 31-44 |
| 09/03/05 | hosting | Fort Hays St | 58-7 |
| 09/10/05 | hosting | Missouri Western | 48-30 |
| 09/17/05 | at | Missouri Southern | 49-20 |
| 09/24/05 | hosting | Emporia St | 52-17 |
| 10/01/05 | at | Washburn | 34-35 |
| 10/08/05 | hosting | Panhandle St | 70-0 |
| 10/15/05 | at | SW Baptist | 70-38 |
| 10/22/05 | at | Truman St | 66-14 |
| 10/29/05 | vs. | NW Missouri St | 56-35 |
| 11/05/05 | at | Central Missouri | 21-83 |
| 11/12/05 | at | Nebraska-Kearney | 49-20 |
| 11/19/05 | at | West Texas A&M | 41-3 |
| 11/26/05 | hosting | NW Missouri St | 10-21 |