| 09/01/05 | hosting | Bacone | 77-7 |
| 09/10/05 | at | Houston | 10-31 |
| 09/17/05 | at | Texas Tech | 21-80 |
| 10/08/05 | hosting | Northwestern State | 6-10 |
| 10/15/05 | at | Nicholls State | 17-37 |
| 10/20/05 | hosting | Stephen F. Austin | 52-24 |
| 10/29/05 | at | McNeese State | 26-31 |
| 11/05/05 | hosting | SE Louisiana St | 35-18 |
| 11/12/05 | at | Northern Colorado | 3-24 |
| 11/19/05 | at | Texas St-San Marcos | 23-26 |