| 09/03/05 | hosting | Benedict | 14-31 |
| 09/10/05 | hosting | Elon | 14-48 |
| 09/17/05 | vs. | Morgan State | 26-55 |
| 09/24/05 | hosting | Howard | 21-39 |
| 10/01/05 | hosting | Norfolk St | 29-58 |
| 10/15/05 | vs. | Bethune-Cookman | 13-56 |
| 10/22/05 | at | Charleston Southern | 28-48 |
| 10/29/05 | hosting | Central St OH | 27-28 |
| 11/05/05 | hosting | Coastal Carolina | 16-42 |
| 11/12/05 | hosting | Gardner-Webb | 21-31 |
| 11/19/05 | at | Hampton | 6-44 |