| 09/03/05 | hosting | Charleston Southern | 28-14 |
| 09/10/05 | at | Florida State | 10-62 |
| 09/24/05 | hosting | Appalachian State | 13-45 |
| 10/01/05 | at | Western Carolina | 17-7 |
| 10/08/05 | at | Mississippi | 7-27 |
| 10/15/05 | hosting | Furman | 31-39 |
| 10/22/05 | at | Georgia Southern | 14-49 |
| 10/29/05 | hosting | Wofford | 10-28 |
| 11/05/05 | at | Chattanooga | 21-31 |
| 11/12/05 | hosting | Elon | 21-0 |
| 11/19/05 | at | VMI | 22-14 |