| 09/02/06 | at | Rose-Hulman | 17-24 |
| 09/09/06 | at | Manchester | 49-35 |
| 09/16/06 | hosting | Anderson | 32-24 |
| 09/30/06 | hosting | Wabash | 15-48 |
| 10/07/06 | at | Wittenberg | 14-28 |
| 10/14/06 | hosting | Oberlin | 31-41 |
| 10/21/06 | at | Kenyon | 30-33 |
| 10/28/06 | hosting | Hiram | 24-16 |
| 11/04/06 | at | Wooster | 31-38 |
| 11/11/06 | hosting | Denison | 16-21 |