| 09/02/06 | hosting | Carnegie Mellon | 6-27 |
| 09/09/06 | at | Bethany WV | 7-42 |
| 09/16/06 | at | Allegheny | 7-52 |
| 09/30/06 | hosting | Oberlin | 14-28 |
| 10/07/06 | at | Kenyon | 34-69 |
| 10/14/06 | hosting | Wooster | 0-52 |
| 10/21/06 | hosting | Denison | 7-42 |
| 10/28/06 | at | Earlham | 16-24 |
| 11/04/06 | at | Ohio Wesleyan | 0-58 |
| 11/11/06 | hosting | Wittenberg | 0-35 |