| 09/02/06 | hosting | East Carolina | 28-23 |
| 09/09/06 | hosting | Massachusetts | 21-20 |
| 09/16/06 | at | Stanford | 37-9 |
| 09/23/06 | hosting | Tulsa | 23-24 OT |
| 09/30/06 | at | Connecticut | 41-17 |
| 10/07/06 | at | Air Force | 24-17 |
| 10/14/06 | hosting | Rutgers | 0-34 |
| 10/28/06 | hosting | Notre Dame | 14-38 |
| 11/04/06 | at | Duke | 38-13 |
| 11/11/06 | at | Eastern Michigan | 49-21 |
| 11/18/06 | hosting | Temple | 42-6 |
| 12/02/06 | hosting | Army | 26-14 |
| 12/30/06 | hosting | Boston College | 24-25 |