| 09/02/06 | hosting | Syracuse | 20-10 |
| 09/09/06 | hosting | Duke | 14-13 |
| 09/16/06 | at | Connecticut | 24-13 |
| 09/23/06 | at | Mississippi | 27-3 |
| 09/30/06 | hosting | Liberty | 34-14 |
| 10/07/06 | hosting | Clemson | 17-27 |
| 10/14/06 | at | North Carolina St | 25-23 |
| 10/28/06 | at | North Carolina | 24-17 |
| 11/04/06 | hosting | Boston College | 21-14 |
| 11/11/06 | at | Florida St | 30-0 |
| 11/18/06 | hosting | Virginia Tech | 6-27 |
| 11/25/06 | at | Maryland | 38-24 |
| 12/02/06 | at | Georgia Tech | 9-6 |
| 01/02/07 | hosting | Louisville | 13-24 |