| 09/02/06 | hosting | Edinboro | 14-28 |
| 09/09/06 | at | Delaware | 7-30 |
| 09/16/06 | at | Clarion | 49-21 |
| 09/23/06 | hosting | Shippensburg | 24-0 |
| 09/30/06 | hosting | Cheyney | 53-12 |
| 10/07/06 | at | Bloomsburg | 27-30 |
| 10/14/06 | hosting | Millersville | 54-27 |
| 10/21/06 | at | Kutztown | 49-47 |
| 10/28/06 | at | East Stroudsburg | 49-28 |
| 11/04/06 | hosting | Mansfield | 44-0 |
| 11/11/06 | at | Slippery Rock | 21-20 |
| 11/18/06 | at | Bryant | 31-29 |
| 11/25/06 | at | Bloomsburg | 20-21 |