| 09/02/06 | at | James Madison | 3-14 |
| 09/09/06 | hosting | California PA | 24-19 |
| 09/16/06 | at | Edinboro | 28-10 |
| 09/23/06 | hosting | Clarion | 24-10 |
| 09/30/06 | at | Shippensburg | 35-14 |
| 10/07/06 | hosting | West Chester | 30-27 |
| 10/14/06 | hosting | Kutztown | 41-14 |
| 10/21/06 | at | Mansfield | 31-7 |
| 10/28/06 | at | Millersville | 28-16 |
| 11/04/06 | hosting | East Stroudsburg | 45-37 |
| 11/11/06 | at | Cheyney | 35-6 |
| 11/25/06 | hosting | West Chester | 21-20 |
| 12/02/06 | at | Shepherd | 24-21 |
| 12/10/06 | at | NW Missouri St | 3-33 |