| 09/02/06 | hosting | Allegheny | 10-35 |
| 09/16/06 | at | Carnegie Mellon | 6-33 |
| 09/23/06 | hosting | Adrian | 27-24 |
| 09/30/06 | at | Grove City | 20-21 |
| 10/07/06 | hosting | Thomas More | 14-42 |
| 10/14/06 | at | Wash & Jeff | 7-50 |
| 10/21/06 | hosting | Bethany WV | 49-13 |
| 10/28/06 | at | Frostburg St | 6-14 |
| 11/04/06 | at | Thiel | 27-45 |
| 11/11/06 | hosting | Waynesburg | 9-21 |