| 09/02/06 | at | Muskingum | 20-45 |
| 09/09/06 | hosting | Hiram | 42-7 |
| 09/16/06 | at | Ohio Wesleyan | 34-28 |
| 09/30/06 | hosting | Thiel | 7-49 |
| 10/07/06 | hosting | Grove City | 34-28 |
| 10/14/06 | at | Waynesburg | 15-41 |
| 10/21/06 | at | Westminster PA | 13-49 |
| 10/28/06 | at | Thomas More | 21-17 |
| 11/04/06 | at | Carnegie Mellon | 6-44 |
| 11/11/06 | hosting | Wash & Jeff | 0-54 |