| 09/03/05 | vs. | Mississippi Valley St | 17-30 |
| 09/10/05 | at | Bethune-Cookman | 17-31 |
| 09/17/05 | hosting | Alabama St | 10-41 |
| 09/24/05 | vs. | Tuskegee | 9-13 |
| 10/01/05 | at | Alcorn St | 17-7 |
| 10/15/05 | hosting | Grambling State | 23-26 |
| 10/22/05 | at | Alabama A&M | 13-28 |
| 10/29/05 | at | Jackson State | 64-36 |
| 11/05/05 | hosting | Prairie View A&M | 7-34 |
| 11/12/05 | hosting | Southern U. | 21-27 |
| 11/19/05 | at | Texas Southern | 40-23 |