| 09/03/05 | at | Wisconsin | 42-56 |
| 09/10/05 | at | Ball State | 40-31 |
| 09/21/05 | at | Boise State | 20-48 |
| 10/01/05 | hosting | Temple | 70-7 |
| 10/08/05 | hosting | Ohio U. | 38-14 |
| 10/15/05 | at | Buffalo | 27-7 |
| 10/22/05 | hosting | Western Michigan | 14-45 |
| 10/29/05 | hosting | Akron | 14-24 |
| 11/05/05 | at | Kent St | 24-14 |
| 11/15/05 | at | Miami OH | 42-14 |
| 11/22/05 | hosting | Toledo | 41-44 2OT |