| 09/02/06 | at | Hiram | 27-6 |
| 09/09/06 | at | Grove City | 28-0 |
| 09/16/06 | hosting | Westminster PA | 33-6 |
| 09/23/06 | hosting | Franklin & Marshall | 34-14 |
| 09/30/06 | hosting | Colorado College | 50-26 |
| 10/14/06 | at | Case Western Reserve | 20-10 |
| 10/21/06 | hosting | Chicago | 27-0 |
| 10/28/06 | at | Washington U. | 10-7 |
| 11/04/06 | hosting | Bethany WV | 44-6 |
| 11/11/06 | at | Thiel | 14-7 |
| 11/18/06 | hosting | Millsaps | 21-0 |
| 11/25/06 | at | Wesley | 0-37 |