| 08/31/06 | at | Youngstown St | 21-51 |
| 09/09/06 | at | Millersville | 27-22 |
| 09/16/06 | hosting | Mansfield | 46-0 |
| 09/23/06 | at | Kutztown | 34-10 |
| 09/30/06 | at | Clarion | 31-7 |
| 10/07/06 | hosting | Shippensburg | 21-28 |
| 10/14/06 | at | California PA | 14-24 |
| 10/21/06 | hosting | Lock Haven | 35-0 |
| 10/28/06 | hosting | Edinboro | 24-21 |
| 11/02/06 | at | Indiana PA | 21-17 |
| 11/11/06 | hosting | West Chester | 20-21 |