| 09/02/06 | hosting | Susquehanna | 6-0 |
| 09/09/06 | at | Albright | 32-13 |
| 09/16/06 | hosting | La Salle | 6-2 |
| 09/30/06 | hosting | McDaniel | 20-0 |
| 10/07/06 | at | Case Western Reserve | 16-7 |
| 10/14/06 | at | Muhlenberg | 6-22 |
| 10/21/06 | at | Gettysburg | 18-27 |
| 10/28/06 | hosting | Johns Hopkins | 17-7 |
| 11/04/06 | at | Franklin & Marshall | 42-10 |
| 11/11/06 | hosting | Dickinson | 31-24 |
| 11/18/06 | hosting | Widener | 7-14 |