| 08/27/05 | at | Johnson C. Smith | 33-9 |
| 09/03/05 | at | Millersville | 20-21 |
| 09/10/05 | at | Charleston WV | 19-14 |
| 09/17/05 | hosting | Shepherd | 13-34 |
| 09/24/05 | at | West Virginia Tech | 82-7 |
| 10/01/05 | at | Fairmont St | 24-3 |
| 10/08/05 | at | Central St OH | 50-20 |
| 10/15/05 | hosting | West Liberty St | 45-21 |
| 10/22/05 | hosting | Concord | 59-15 |
| 10/29/05 | at | West Virginia St | 49-20 |
| 11/05/05 | hosting | WV Wesleyan | 38-10 |