| 09/10/05 | hosting | Alabama A&M | 44-0 |
| 09/17/05 | vs. | Washington State | 7-48 |
| 10/01/05 | vs. | Prairie View A&M | 56-7 |
| 10/08/05 | hosting | Mississippi Valley St | 37-22 |
| 10/15/05 | at | Arkansas-Pine Bluff | 26-23 |
| 10/22/05 | at | Jackson State | 52-21 |
| 10/29/05 | hosting | Texas Southern | 58-21 |
| 11/05/05 | at | Alabama St | 32-27 |
| 11/12/05 | hosting | Concordia AL | 82-7 |
| 11/26/05 | vs. | Southern U. | 50-35 |
| 12/03/05 | at | Alcorn St | 46-19 |
| 12/10/05 | vs. | Alabama A&M | 45-6 |