| 09/03/05 | hosting | Merrimack | 0-35 |
| 09/10/05 | at | Plymouth St | 7-14 |
| 09/17/05 | hosting | Bridgewater St MA | 7-48 |
| 09/24/05 | at | Curry | 6-34 |
| 10/01/05 | hosting | Endicott | 14-16 |
| 10/08/05 | at | Nichols | 28-7 |
| 10/15/05 | hosting | MIT | 34-6 |
| 10/22/05 | hosting | Western New England | 17-3 |
| 10/29/05 | at | Mass Maritime | 37-27 |
| 11/05/05 | at | Salve Regina | 28-14 |