| 09/02/05 | at | Curry | 18-23 |
| 09/10/05 | at | WPI | 17-28 |
| 09/16/05 | hosting | Salve Regina | 28-27 |
| 09/24/05 | at | MIT | 49-6 |
| 09/30/05 | hosting | Westfield St | 47-7 |
| 10/08/05 | at | Framingham St | 37-0 |
| 10/15/05 | hosting | Mass Maritime | 27-7 |
| 10/22/05 | at | Maine Maritime | 7-35 |
| 10/29/05 | hosting | Bridgewater St MA | 20-24 |
| 11/05/05 | at | Fitchburg St | 17-20 |