| 09/02/06 | hosting | Pittsburg St | 12-52 |
| 09/09/06 | at | Angelo St | 20-6 |
| 09/16/06 | hosting | Eastern New Mexico | 15-24 |
| 09/23/06 | at | Midwestern St | 14-63 |
| 09/30/06 | hosting | Northeastern St OK | 29-40 |
| 10/05/06 | at | Central Oklahoma | 0-37 |
| 10/14/06 | hosting | TAMU-Kingsville | 34-37 |
| 10/28/06 | at | TAMU-Commerce | 10-3 |
| 11/04/06 | hosting | SW Oklahoma St | 28-38 |
| 11/11/06 | at | SE Oklahoma St | 6-42 |