| 08/31/06 | hosting | Missouri Western | 29-32 |
| 09/07/06 | at | Abilene Christian | 18-24 |
| 09/16/06 | hosting | Angelo St | 30-24 |
| 09/23/06 | at | Eastern New Mexico | 19-16 |
| 09/30/06 | hosting | TAMU-Commerce | 10-3 |
| 10/05/06 | hosting | East Central OK | 37-0 |
| 10/14/06 | hosting | NW Oklahoma St | 31-26 |
| 10/21/06 | hosting | SE Oklahoma St | 7-9 |
| 10/28/06 | at | SW Oklahoma St | 22-25 |
| 11/04/06 | hosting | West Texas A&M | 7-38 |
| 11/11/06 | at | Northeastern St OK | 23-26 |