| 08/31/06 | at | Drake | 48-7 |
| 09/09/06 | hosting | North Dakota | 31-35 |
| 09/16/06 | hosting | South Dakota St | 27-17 |
| 09/30/06 | at | Iowa St | 27-28 |
| 10/07/06 | hosting | Missouri St | 38-7 |
| 10/14/06 | at | Indiana St | 34-14 |
| 10/21/06 | at | Youngstown St | 31-23 |
| 10/28/06 | hosting | Western Illinois | 13-24 |
| 11/04/06 | hosting | Western Kentucky | 31-20 |
| 11/11/06 | at | Southern Illinois | 23-47 |
| 11/18/06 | hosting | Illinois St | 38-27 |