| 09/02/06 | at | Texas St-San Marcos | 23-27 |
| 09/09/06 | hosting | SE Oklahoma St | 30-37 |
| 09/23/06 | at | TAMU-Commerce | 13-14 |
| 09/30/06 | at | SW Oklahoma St | 21-19 |
| 10/07/06 | hosting | TAMU-Kingsville | 23-0 |
| 10/14/06 | at | Midwestern St | 38-17 |
| 10/21/06 | hosting | Eastern New Mexico | 48-0 |
| 10/28/06 | at | Abilene Christian | 37-36 |
| 11/04/06 | hosting | Angelo St | 41-10 |
| 11/11/06 | at | West Texas A&M | 16-21 |