| 09/02/06 | hosting | SMU | 35-3 |
| 09/09/06 | at | UTEP | 38-35 OT |
| 09/16/06 | at | TCU | 3-12 |
| 09/23/06 | hosting | SE Louisiana St | 62-0 |
| 09/30/06 | at | Texas A&M | 31-27 |
| 10/07/06 | hosting | Missouri | 21-38 |
| 10/14/06 | at | Colorado | 6-30 |
| 10/21/06 | at | Iowa St | 42-26 |
| 10/28/06 | hosting | Texas | 31-35 |
| 11/04/06 | hosting | Baylor | 55-21 |
| 11/11/06 | at | Oklahoma | 24-34 |
| 11/18/06 | hosting | Oklahoma St | 30-24 |
| 12/29/06 | hosting | Minnesota | 44-41 |