| 09/17/05 | at | Fordham | 23-17 |
| 09/24/05 | hosting | Duquesne | 23-13 |
| 10/01/05 | at | Princeton | 3-43 |
| 10/08/05 | at | Lafayette | 7-14 |
| 10/15/05 | hosting | Pennsylvania | 16-44 |
| 10/22/05 | at | Dartmouth | 6-17 |
| 10/29/05 | hosting | Yale | 3-37 |
| 11/05/05 | hosting | Harvard | 7-55 |
| 11/12/05 | at | Cornell NY | 7-45 |
| 11/19/05 | hosting | Brown | 21-52 |