| 09/17/05 | hosting | Duquesne | 41-14 |
| 09/24/05 | vs. | Villanova | 24-28 |
| 10/01/05 | at | Dartmouth | 26-9 |
| 10/08/05 | hosting | Bucknell | 53-7 |
| 10/15/05 | at | Columbia | 44-16 |
| 10/22/05 | hosting | Yale | 38-21 |
| 10/29/05 | at | Brown | 20-34 |
| 11/05/05 | hosting | Princeton | 13-30 |
| 11/12/05 | at | Harvard | 3-29 |
| 11/19/05 | hosting | Cornell NY | 7-16 |