| 09/10/05 | hosting | Benedictine IL | 44-27 |
| 09/17/05 | at | Augsburg | 64-25 |
| 09/24/05 | at | Washington U. | 25-0 |
| 10/01/05 | hosting | Wheaton | 35-26 |
| 10/08/05 | at | Illinois Wesleyan | 36-14 |
| 10/15/05 | hosting | Carthage | 43-24 |
| 10/22/05 | at | Elmhurst | 28-21 |
| 10/29/05 | hosting | Millikin | 52-14 |
| 11/05/05 | at | Augustana IL | 17-20 |
| 11/12/05 | hosting | North Park | 49-7 |
| 11/19/05 | hosting | Capital | 19-21 |