| 09/03/05 | at | Hampden-Sydney | 7-52 |
| 09/10/05 | hosting | Huntingdon | 6-23 |
| 09/17/05 | hosting | Washington and Lee | 7-10 |
| 09/24/05 | at | Maryville | 33-14 |
| 10/01/05 | hosting | Centre | 31-28 |
| 10/08/05 | hosting | DePauw | 0-34 |
| 10/22/05 | at | Rose-Hulman | 20-7 |
| 10/29/05 | at | Millsaps | 19-16 |
| 11/05/05 | hosting | Trinity TX | 3-17 |
| 11/12/05 | at | Rhodes | 25-22 |