| 09/10/05 | hosting | Alfred | 36-22 |
| 09/17/05 | at | Sewanee | 10-7 |
| 09/24/05 | hosting | Centre | 26-35 |
| 10/01/05 | at | Randolph-Macon | 44-7 |
| 10/08/05 | hosting | Catholic | 27-24 |
| 10/15/05 | at | Hampden-Sydney | 38-34 |
| 10/22/05 | at | Guilford | 26-28 |
| 10/29/05 | hosting | Bridgewater VA | 13-17 |
| 11/05/05 | at | Emory & Henry | 45-7 |
| 11/12/05 | hosting | Case Western Reserve | 34-10 |