| 08/26/05 | hosting | Clarion | 43-14 |
| 09/03/05 | at | North Dakota | 7-41 |
| 09/10/05 | hosting | Indiana PA | 30-20 |
| 09/17/05 | at | Delaware | 21-42 |
| 09/24/05 | hosting | Cheyney | 64-0 |
| 10/01/05 | at | Kutztown | 48-21 |
| 10/08/05 | at | Millersville | 27-7 |
| 10/15/05 | hosting | Mansfield | 63-20 |
| 10/22/05 | hosting | East Stroudsburg | 18-17 |
| 10/29/05 | at | Bloomsburg | 35-42 |
| 11/05/05 | at | Shippensburg | 24-16 |
| 11/12/05 | at | C.W. Post | 20-24 |