| 08/27/05 | at | Shaw | 45-24 |
| 09/01/05 | vs. | West Georgia | 14-10 |
| 09/15/05 | vs. | West Virginia Tech | 71-9 |
| 09/24/05 | at | Mars Hill | 7-14 |
| 10/01/05 | at | Newberry | 41-28 |
| 10/08/05 | hosting | Presbyterian | 3-37 |
| 10/15/05 | at | Tusculum | 38-0 |
| 10/22/05 | hosting | Lenoir-Rhyne | 33-6 |
| 10/27/05 | hosting | Catawba | 33-21 |
| 11/05/05 | at | Wingate | 47-14 |