| 08/27/05 | at | Winston-Salem St | 20-10 |
| 09/03/05 | hosting | Livingstone | 38-6 |
| 09/10/05 | at | Virginia St | 37-18 |
| 09/17/05 | hosting | Indiana PA | 16-19 |
| 09/24/05 | at | Presbyterian | 7-37 |
| 10/01/05 | hosting | Mars Hill | 31-0 |
| 10/08/05 | at | Wingate | 30-24 |
| 10/15/05 | hosting | Newberry | 37-43 |
| 10/22/05 | hosting | Tusculum | 28-20 |
| 10/27/05 | at | Carson-Newman | 21-33 |
| 11/05/05 | hosting | Lenoir-Rhyne | 13-17 |