| 09/03/05 | at | Kentucky St | 32-27 |
| 09/10/05 | hosting | North Carolina Central | 21-28 |
| 09/17/05 | at | Davidson | 16-9 |
| 09/24/05 | at | Newberry | 27-24 |
| 10/01/05 | at | Wingate | 7-28 |
| 10/08/05 | hosting | Mars Hill | 21-33 |
| 10/15/05 | hosting | Presbyterian | 0-20 |
| 10/22/05 | at | Carson-Newman | 6-33 |
| 10/29/05 | hosting | Tusculum | 21-7 |
| 11/05/05 | at | Catawba | 17-13 |