| 09/02/06 | at | Penn State | 16-34 |
| 09/09/06 | at | North Carolina St | 20-17 |
| 09/16/06 | at | Central Michigan | 21-24 |
| 09/23/06 | hosting | North Texas | 33-13 |
| 09/30/06 | at | Kent St | 15-37 |
| 10/07/06 | at | Cincinnati | 14-20 |
| 10/21/06 | hosting | Miami OH | 24-13 |
| 10/28/06 | at | Toledo | 20-35 |
| 11/04/06 | hosting | Bowling Green | 35-28 |
| 11/09/06 | hosting | Buffalo | 31-16 |
| 11/16/06 | at | Ohio U. | 7-17 |
| 11/24/06 | hosting | Western Michigan | 0-17 |