| 09/02/06 | hosting | Tennessee-Martin | 29-3 |
| 09/09/06 | at | Northern Illinois | 35-23 |
| 09/16/06 | at | Rutgers | 7-24 |
| 09/23/06 | at | Missouri | 6-31 |
| 09/30/06 | hosting | Bowling Green | 9-21 |
| 10/07/06 | hosting | Western Michigan | 27-20 |
| 10/14/06 | at | Illinois | 20-17 |
| 10/21/06 | hosting | Buffalo | 42-7 |
| 10/28/06 | at | Kent St | 17-7 |
| 11/04/06 | at | Eastern Michigan | 16-10 |
| 11/16/06 | hosting | Akron | 17-7 |
| 11/24/06 | at | Miami OH | 34-24 |
| 11/30/06 | at | Central Michigan | 10-31 |
| 01/07/07 | at | Southern Miss | 7-28 |