| 09/03/05 | at | Oberlin | 30-27 |
| 09/10/05 | hosting | Denison | 20-6 |
| 09/17/05 | at | Kenyon | 19-8 |
| 09/24/05 | hosting | Wooster | 21-38 |
| 10/01/05 | hosting | Defiance | 13-14 |
| 10/15/05 | hosting | Washington U. | 7-28 |
| 10/22/05 | hosting | Alfred | 0-14 |
| 10/29/05 | at | Carnegie Mellon | 20-23 |
| 11/05/05 | at | Chicago | 7-14 |
| 11/12/05 | at | Washington and Lee | 10-34 |