| 09/03/05 | vs. | Jackson State | 20-7 |
| 09/10/05 | at | Howard | 22-12 |
| 09/15/05 | at | North Carolina A&T | 31-14 |
| 09/24/05 | vs. | Morgan State | 44-14 |
| 10/01/05 | hosting | Delaware St | 26-8 |
| 10/08/05 | at | Gardner-Webb | 52-21 |
| 10/15/05 | at | Norfolk St | 55-14 |
| 10/22/05 | hosting | South Carolina St | 14-10 |
| 11/05/05 | at | Bethune-Cookman | 24-10 |
| 11/12/05 | hosting | Florida A&M | 34-14 |
| 11/19/05 | hosting | Savannah State | 44-6 |
| 11/26/05 | hosting | Richmond | 10-38 |